Urantide should be considered a low efficacy partial agonist.

2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Urantide mimics urotensin-II induced calcium release in cells expressing recombinant UT receptors.

"Urotensin-II is the natural ligand of the UT receptor. This novel system is involved in the regulation of cardiovascular functions. Recently, a urotensin-II analog ([Pen[superscript]5,DTrp[superscript]7,Orn[superscript]8]urotensin-II(4-11)), named urantide, has been proposed as a selective and potent UT receptor antagonist," scientists writing in the European Journal of Pharmacology report.

V. Camarda and colleagues of the University of Ferrara wrote, "In order to pharmacologically characterize this new compound, …