Researchers from Seoul National University, Medical Department describe findings in glioma.

According to recent research from Seoul, South Korea, "CKD-602 7-[2-(N-isopropylamino)ethyl]-(20S)camptothecin, belotecan) is a synthetic water-soluble camptothecin derivative and topoisornerase inhibitor that has been shown to have clinical anticancer effect against ovarian and lung cancer. We studied its anticancer effects oil four human glioma cell lines, U87 MG, U343 MG, U251 MG and LN229."

"Cell viability was quantified by a modified 2-(2-methoxy-4-methoxy)-3-(4-nitropheyl)-5-(2,4-disulfophellyl) -2H-tetrazolium, monosodium salt and significant time- and dose-dependent cytotoxicity was observed in all cell lines. Susceptibility to CKD-602 at 48 h after treatment …